SCHEMBL287439

SCHEMBL287439

[CH2]C(=O)NCCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497606 0.83
SCHEMBL997383 0.81
SCHEMBL6163193 0.79 EPHX1 (0.67)
SCHEMBL2834328 0.79 EPHX1 (0.50)
SCHEMBL7862965 0.79 EPHX1 (0.67)
SCHEMBL4722784 0.79 EPHX1 (0.67)
SCHEMBL6164184 0.79 EPHX1 (0.67)
SCHEMBL11326795 0.79 EPHX1 (0.67)
SCHEMBL6161277 0.79 EPHX1 (0.67)
SCHEMBL4744400 0.79 EPHX1 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 823 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239759-A1 ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS INTERVET INC. (US) 2024-07-18 US claimed
US-20240209129-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. 2024-06-27 US claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
WO-2024116106-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. (US) 2024-06-06 WO claimed
CN-111295376-B Injectable isoxazoline pharmaceutical composition and use thereof against parasite infestations 英特维特国际股份有限公司 2024-05-24 CN claimed
EP-4358941-A1 PALATABLE VETERINARY COMPOSITIONS Intervet International B.V. (NL) 2024-05-01 EP claimed
US-20240122849-A1 ISOXAZOLINE COMPOSITIONS AND USE THEREOF IN THE PREVENTION OR TREATMENT OF PARASITE INFESTATIONS IN ANIMALS INTERVET INC. (US) 2024-04-18 US claimed
EP-4351341-A1 TICK CONTROL METHODS Intervet International B.V. (NL) 2024-04-17 EP claimed
CN-117545473-A Palatable veterinary compositions 英特维特国际股份有限公司 2024-02-09 CN claimed
EP-4316522-A2 INJECTABLE ISOXAZOLINE PHARMACEUTICAL COMPOSITIONS AND THEIR USE AGAINST PARASITE INFESTATION Intervet International B.V. (NL) 2024-02-07 EP claimed
WO-2009024541-A2 ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS INTERVET INTERNATIONAL B.V. (NL) 2009-02-26 WO claimed
WO-2008112674-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2008-09-18 WO claimed
WO-2008076754-A2 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2008-06-26 WO claimed
US-20070259852-A1 BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS IRM LLC 2007-11-08 US claimed
US-7253164-B2 Bicyclic compounds and compositions as PDF inhibitors IRM LLC (BM) 2007-08-07 US claimed
US-20050197326-A1 Bicyclic compounds and compostions as PDF inhibitors IRM LLC 2005-09-08 US claimed
US-5270311-A [1,2,4]-Triazolo[1,5-a]and pyrazolo[2,3-a][1,3,5]triazine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-14 US claimed
US-5219857-A Method of treating cognitive and related neural behavioral problems AMERICAN CYANAMID COMPANY (US) 1993-06-15 US claimed
US-5126340-A Antidepressants AMERICAN CYANAMID COMPANY (US) 1992-06-30 US claimed
EP-0459702-A1 Azole Derivatives ZENECA LIMITED (GB) 1991-12-04 EP claimed