Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefonicid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.99 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.76 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.76 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
| ▸ | PGR | P06401 | 1/20 | 0.76 |
| ▸ | PPARG | P37231 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | POLB | P06746 | 9/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefonicid SCHEMBL60350 | 0.99 | SLC6A4 (1.00) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL537693 | 0.99 | SLC6A4 (1.00) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL16072827 | 0.99 | SLC6A4 (1.00) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL18048103 | 0.99 | SLC6A4 (1.00) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL9080022 | 0.99 | SLC6A4 (1.00) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL13297839 | 0.99 | SLC6A4 (1.00) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL8425120 | 0.99 | SLC6A4 (0.99) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL27856008 | 0.99 | SLC6A4 (0.99) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL41894 | 0.99 | SLC6A4 (0.99) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 | |
| Cefonicid SCHEMBL27865839 | 0.99 | SLC6A4 (0.99) | SLC6A4SLC22A6SLC22A8SLC22A11NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102283847-A | Cefonicid compound preparation and preparation method thereof | — | 2011-12-21 | — | — | CN | disclosed |
| CN-1247200-C | Cefonicid sodium antibacterial composition | SHENZHEN XINLITAI PARMACEUTICA (CN) | 2006-03-29 | — | — | CN | disclosed |
| CN-1520821-A | Cefonicid sodium antibacterial composition | 深圳信立泰药业有限公司 | 2004-08-18 | — | — | CN | disclosed |