Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.65 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528924 | 0.92 | PTGS2 (0.69) | PTGS2PTGS1CYP2C9PDPK1PTGES | |
| SCHEMBL27552855 | 0.88 | PTGS2 (0.64) | PTGS2PTGS1CYP2C9PDPK1PTGES | |
| SCHEMBL27552901 | 0.88 | PTGS2 (0.64) | PTGS2PTGS1CYP2C9PDPK1PTGES | |
| SCHEMBL27553014 | 0.86 | PTGS2 (0.64) | PTGS2PTGS1CYP2C9PDPK1PTGES | |
| SCHEMBL27528930 | 0.86 | PTGS2 (0.64) | PTGS2PTGS1CYP2C9PDPK1PTGES | |
| SCHEMBL27528885 | 0.86 | PTGS2 (0.49) | PTGS2PTGS1CYP2C9ALOX5 | |
| SCHEMBL7876663 | 0.84 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9PDPK1PTGES | |
| SCHEMBL27528922 | 0.84 | PTGS2 (0.56) | PTGS2PTGS1ABCB11 | |
| SCHEMBL27552913 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1CYP2C9ALOX5 | |
| SCHEMBL7876247 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9PDPK1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1271347-A | 1, 5-diphenylpyrazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-10-25 | — | — | CN | disclosed |