Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23021686 | 0.88 | KDM4E (0.61) | HSP90AA1KDM4EHPGDHTTMAPT | |
| SCHEMBL6864124 | 0.86 | HSP90AA1 (0.59) | HSP90AA1KDM4EHPGDHTTMAPT | |
| SCHEMBL17743610 | 0.76 | HSP90AA1 (0.61) | HSP90AA1KDM4EHPGDHTTTSHR | |
| SCHEMBL487433 | 0.76 | KDM4E (0.75) | HSP90AA1KDM4EHPGDHTTMAPT | |
| SCHEMBL6862139 | 0.75 | KMT2A (0.54) | KDM4EHPGDHTTMAPTTSHR | |
| SCHEMBL11960951 | 0.75 | HPGD (0.62) | HSP90AA1KDM4EHPGDHTTMAPT | |
| SCHEMBL19657107 | 0.73 | KDM4E (0.51) | HSP90AA1KDM4EHPGDHTTMAPT | |
| SCHEMBL29951614 | 0.73 | KDM4E (0.67) | HSP90AA1KDM4EHPGDHTTMAPT | |
| SCHEMBL23021674 | 0.73 | HPGD (0.61) | HSP90AA1HPGDHTTTSHRALDH1A1 | |
| SCHEMBL2458251 | 0.73 | HTT (0.51) | KDM4EHPGDHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1259120-A | Calcilytic compounds | SMITHKLINE BEECHAM CORP (US) | 2000-07-05 | — | — | CN | disclosed |