Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28745361 | 1.00 | KLK7 (0.43) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL12076369 | 0.87 | MAPT (0.52) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL6511442 | 0.87 | MAPT (0.52) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL29931085 | 0.83 | HTT (0.54) | KLK7KLK5MAPTKEAP1NFE2L2 | |
| SCHEMBL3898159 | 0.80 | MAPT (0.50) | KLK7KLK5MAPTKEAP1NFE2L2 | |
| SCHEMBL8574390 | 0.76 | MAPT (0.47) | KLK7KLK5MAPTKEAP1NFE2L2 | |
| SCHEMBL8574384 | 0.76 | MAPT (0.47) | KLK7KLK5MAPTKEAP1NFE2L2 | |
| SCHEMBL31300270 | 0.75 | MAPT (0.52) | KLK7KLK5MAPTKEAP1NFE2L2 | |
| SCHEMBL29396217 | 0.75 | HTT (0.56) | MAPTKEAP1NFE2L2HTTDPP8 | |
| SCHEMBL28770709 | 0.74 | KMT2A (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100371323-C | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-02-27 | — | — | CN | disclosed |
| CN-1298703-C | Cyanopyrrolidine Derivatives | TAISHO PHARMACENTICAL CO LTD (JP) | 2007-02-07 | — | — | CN | disclosed |
| CN-1772733-A | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2006-05-17 | — | — | CN | disclosed |
| CN-1715269-A | Cyanopyrrolidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2006-01-04 | — | — | CN | disclosed |
| CN-1474809-A | Cyanopyrrolidine Derivatives | ������ҩ��ʽ���� | 2004-02-11 | — | — | CN | disclosed |