Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073685 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL16672506 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL13469252 | 0.84 | ALDH1A1 (0.67) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL1790360 | 0.83 | TSHR (0.65) | ALDH1A1TDP1L3MBTL1TSHRMAPK1 | |
| SCHEMBL6343540 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL227321 | 0.83 | TSHR (0.59) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL14844169 | 0.83 | ALDH1A1 (0.74) | ALDH1A1TDP1TSHRCYP3A4KMT2A | |
| SCHEMBL24548542 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL27526992 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL3413098 | 0.81 | ALDH1A1 (0.77) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616225-A | Treprostinil prodrugs | 联合治疗公司 | 2022-06-10 | — | — | CN | disclosed |