Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81434 | 0.82 | POLB (0.75) | POLBKDM4EGAANPC1RAB9A | |
| SCHEMBL29521664 | 0.82 | POLB (0.75) | POLBKDM4EGAANPC1RAB9A | |
| SCHEMBL654224 | 0.81 | MAPT (0.50) | POLBKDM4EGAAALDH1A1MAPT | |
| SCHEMBL29892467 | 0.81 | MAPT (0.61) | POLBKDM4EGAANPC1RAB9A | |
| SCHEMBL1140606 | 0.81 | MAPT (0.61) | POLBKDM4EGAANPC1RAB9A | |
| Phosphine SCHEMBL30387635 | 0.80 | POLB (0.72) | POLBKDM4EGAANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27918048 | 0.80 | POLB (0.72) | POLBKDM4EGAANPC1RAB9A | |
| SCHEMBL14889779 | 0.79 | POLB (0.56) | POLBKDM4EGAANPC1RAB9A | |
| SCHEMBL9685670 | 0.78 | POLB (0.54) | POLBKDM4EGAANPC1RAB9A | |
| Formaldehyde SCHEMBL27427139 | 0.78 | MAPT (0.58) | POLBKDM4EGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1355697-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | CN | disclosed |