Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28748824 | 1.00 | HSD11B1 (0.70) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL12237251 | 0.88 | HSD11B1 (0.71) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL28397073 | 0.88 | HSD11B1 (0.71) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL28748984 | 0.88 | HSD11B1 (0.71) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL28748903 | 0.83 | HSD11B1 (0.66) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL28748814 | 0.83 | HSD11B1 (0.66) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL28398933 | 0.83 | HSD11B1 (0.66) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL11173507 | 0.83 | HSD11B1 (0.66) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL28398931 | 0.83 | HSD11B1 (0.66) | HSD11B1GAACYP1A2CYP2C19TDP1 | |
| SCHEMBL28748844 | 0.83 | HSD11B1 (0.66) | HSD11B1GAACYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116769741-B | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-116769741-A | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769741-B | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114540321-B | Preparation method of R-2-sulfonyl-1-phenylethanol derivative | 沈阳药科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-116769741-A | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-114540321-A | Preparation method of R-2-sulfonyl-1-phenylethanol derivative | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |