Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30657566 | 0.85 | EPHX1 (0.55) | EPHX1OPRM1KCNH2TAAR1SLC6A2 | |
| SCHEMBL11615146 | 0.82 | KCNH2 (0.49) | EPHX1OPRM1KCNH2TAAR1SLC6A2 | |
| SCHEMBL1665737 | 0.78 | EPHX1 (0.48) | EPHX1OPRM1KCNH2TAAR1SLC6A2 | |
| SCHEMBL8778520 | 0.76 | EPHX1 (0.73) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL21677972 | 0.76 | TRPA1 (0.50) | EPHX1OPRM1KCNH2TAAR1SLC6A2 | |
| SCHEMBL4679591 | 0.76 | EPHX1 (0.52) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL22660956 | 0.76 | EPHX1 (0.46) | EPHX1OPRM1KCNH2TAAR1SLC6A2 | |
| SCHEMBL5001745 | 0.76 | EPHX1 (0.52) | EPHX1TAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL5597661 | 0.76 | TRPA1 (0.54) | EPHX1OPRM1KCNH2TAAR1SLC6A2 | |
| SCHEMBL5597658 | 0.76 | TRPA1 (0.54) | EPHX1OPRM1KCNH2TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1499972-A | Imidazolyl derivatives as corticotropin releasing factor inhibitors | ����˹�ж�-����˹˹������˾ | 2004-05-26 | — | — | CN | disclosed |