Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510602 | 1.00 | CMA1 (0.58) | CMA1ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL13104375 | 0.89 | CMA1 (0.73) | CMA1ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL26667208 | 0.81 | NPSR1 (0.50) | CMA1ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL13820085 | 0.80 | CMA1 (0.56) | CMA1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18101274 | 0.76 | CMA1 (0.51) | CMA1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL18101221 | 0.76 | CMA1 (0.51) | CMA1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL18101266 | 0.76 | CMA1 (0.51) | CMA1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL18101271 | 0.76 | CMA1 (0.51) | CMA1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL3188905 | 0.75 | ALDH1A1 (0.54) | CMA1ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL3192381 | 0.73 | ALDH1A1 (0.58) | CMA1ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114432301-B | Covalent inhibitor derivative and application thereof in treatment of viral infection | 北京大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-114432301-A | Covalent inhibitor derivative and application thereof in treating virus infection | 北京大学 | 2022-05-06 | — | — | CN | disclosed |