Bromobenzene

Bromobenzene

SCHEMBL28753154

Brc1ccccc1.C1CCC1

nearest known ligand 0.79

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.79
TDP1 Q9NUW8 2/20 0.79
MAPK1 P28482 4/20 0.53
CYP2A6 P11509 2/20 0.47
HTR2A P28223 1/20 0.39
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.36
NFKB1 P19838 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
ALOX15 P16050 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromobenzene SCHEMBL1331681 0.89
Bromobenzene SCHEMBL20537325 0.89 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1CYP2A6HTR2A
Bromobenzene SCHEMBL537562 0.89 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1CYP2A6HTR2A
Bromobenzene SCHEMBL1331176 0.89
Bromobenzene SCHEMBL2158200 0.89
Bromobenzene SCHEMBL1332317 0.89
Bromobenzene SCHEMBL1542 0.89
SCHEMBL24508036 0.85 ALDH1A1 (0.92) ALDH1A1TDP1MAPK1CYP2A6HTR2A
Bromobenzene SCHEMBL11077625 0.85
Bromobenzene SCHEMBL22390537 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100475758-C Full conjugation type monomer of dibenzo cyclobutene and preparation method thereof UNIV SICHUAN (CN) 2009-04-08 CN disclosed
CN-1562924-A Full conjugation type monomer of dibenzo cyclobutene and preparation method UNIV SICHUAN (CN) 2005-01-12 CN disclosed