Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383496 | 0.77 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL9637850 | 0.77 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL9052472 | 0.77 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL20710812 | 0.76 | KMT2A (0.41) | TSHRALDH1A1MAOBMAPK1LTA4H | |
| SCHEMBL673603 | 0.73 | TSHR (0.44) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL10807891 | 0.73 | TSHR (0.44) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL9407989 | 0.73 | MAOB (0.43) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL11437153 | 0.73 | CA2 (0.37) | TSHRIDO1AGXTALDH1A1CA2 | |
| SCHEMBL2931114 | 0.72 | TP53 (0.44) | TSHRIDO1AGXTALDH1A1MAPT | |
| SCHEMBL14702031 | 0.72 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475888-C | Flame retardant polyester compositions for calendering | EASTMAN CHEM CO (US) | 2009-04-08 | — | — | CN | disclosed |
| CN-1974659-A | Flame retardant polyester compositions for calendering, flame retardant thin film or sheet and production method thereof | EASTMAN CHEM CO (US) | 2007-06-06 | — | — | CN | disclosed |
| CN-1729240-A | Flame retardant polyester compositions for calendering | EASTMAN CHEM CO (US) | 2006-02-01 | — | — | CN | disclosed |