Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894208 | 0.91 | TSHR (0.38) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL107215 | 0.85 | TSHR (0.37) | TSHRHPGD | |
| SCHEMBL22344273 | 0.81 | TSHR (0.47) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL28332584 | 0.79 | TSHR (0.39) | TSHRHPGD | |
| SCHEMBL9742440 | 0.79 | TSHR (0.39) | TSHRHPGD | |
| SCHEMBL9627896 | 0.78 | TSHR (0.47) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL18123487 | 0.76 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL5606323 | 0.75 | ALDH1A1 (0.35) | ALDH1A1CYP3A4HCAR2 | |
| SCHEMBL27516602 | 0.75 | TSHR (0.58) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL1398238 | 0.75 | TSHR (0.56) | TSHRHPGDTHRBCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527595-B | Functionalized organic silicon resin and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2022-06-07 | — | — | CN | disclosed |
| CN-113527595-A | Functionalized organic silicon resin and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2021-10-22 | — | — | CN | disclosed |