Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | ARG1 | P05089 | 3/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL5057619 | 0.83 | SLC1A2 (0.42) | SLC1A2SLC1A1GRIK1GRIK2ARG1 | |
| Lysine SCHEMBL3273758 | 0.83 | GSR (0.56) | SLC1A2ARG1ARG2DPP4 | |
| Aspartic Acid SCHEMBL8016849 | 0.82 | GRIK1 (0.42) | SLC1A2GRIK1GRIK2ARG1ARG2 | |
| SCHEMBL2888794 | 0.82 | SLC1A2 (0.41) | SLC1A2SLC1A1GRIK1GRIK2SLC1A3 | |
| Cysteine SCHEMBL8631390 | 0.82 | PTGS1 (0.50) | SLC1A2GRIK1GRIK2ARG1ARG2 | |
| SCHEMBL27561309 | 0.82 | SLC1A2 (0.36) | SLC1A2SLC1A1GRIK1GRIK2SLC1A3 | |
| Alanine SCHEMBL7049985 | 0.81 | SLC1A2 (0.46) | SLC1A2SPHK1ARG1ARG2 | |
| Asparagine SCHEMBL8942998 | 0.81 | GRIK1 (0.41) | SLC1A2GRIK1GRIK2ARG1ARG2 | |
| Aspartic Acid SCHEMBL135826 | 0.79 | GRIK1 (0.38) | SLC1A2GRIK1GRIK2ARG1ARG2 | |
| Sarcosine SCHEMBL7363670 | 0.79 | SLC1A2 (0.33) | SLC1A2GRIK1GRIK2SPHK1ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1655792-A | Combination product of a 1,4-benzothiepine 1,1-dioxide compound with at least one other active ingredient and the use of the product | AVENTIS PHARMA GMBH (DE) | 2005-08-17 | — | — | CN | disclosed |
| CN-1638801-A | Combination preparations of aryl substituted propanolamine derivatives with other active ingredients and the use thereof | AVENTIS PHARMA GMBH (DE) | 2005-07-13 | — | — | CN | disclosed |