Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | ARG1 | P05089 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL8016849 | 0.93 | GRIK1 (0.42) | GRIK1GRIK2SLC1A2ARG1MEN1 | |
| Aspartic Acid SCHEMBL2880117 | 0.83 | GRIK1 (0.33) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| Asparagine SCHEMBL8942998 | 0.83 | GRIK1 (0.41) | GRIK1GRIK2SLC1A2ARG1MEN1 | |
| SCHEMBL628704 | 0.82 | SLC1A2 (0.50) | SLC1A2ARG1MEN1KMT2AARG2 | |
| SCHEMBL2888794 | 0.81 | SLC1A2 (0.41) | GRIK1GRIK2SLC1A2ARG1MEN1 | |
| Serine SCHEMBL5057619 | 0.80 | SLC1A2 (0.42) | GRIK1GRIK2SLC1A2ARG1MEN1 | |
| Norvaline SCHEMBL28754255 | 0.79 | SLC1A2 (0.39) | GRIK1GRIK2SLC1A2ARG1ARG2 | |
| Cysteine SCHEMBL8631390 | 0.79 | PTGS1 (0.50) | GRIK1GRIK2SLC1A2ARG1MEN1 | |
| Leucine SCHEMBL6370664 | 0.78 | SLC7A5 (0.42) | GRIK1GRIK2SLC1A2ARG1 | |
| Alanine SCHEMBL7049985 | 0.78 | SLC1A2 (0.46) | SLC1A2ARG1MEN1KMT2AARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3881819-B1 | TWO-DOSAGE-FORM ESSENCE AND PREPARATION METHOD THEREFOR | GUANGZHOU BIOHOPE CO LTD (CN) | 2024-12-25 | — | — | EP | claimed |
| US-20230240963-A1 | PIGMENT SUSPENSION AND COSMETIC AGENT PREPARED USING THE PIGMENT SUSPENSION | HENKEL AG & CO. KGAA (DE) | 2023-08-03 | — | — | US | claimed |
| EP-4171471-A2 | PIGMENT SUSPENSION AND COSMETIC AGENT PREPARED USING THE PIGMENT SUSPENSION | Henkel AG & Co. KGaA (DE) | 2023-05-03 | — | — | EP | claimed |
| EP-4171499-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DERIVATIVE OF ALKYLATED SILANOL, A COLORING COMPOUND AND A POST-TREATMENT AGENT | Henkel AG & Co. KGaA (DE) | 2023-05-03 | — | — | EP | claimed |
| CN-110013447-B | Cream for removing striae gravidarum and preparation method thereof | 广州雅纯化妆品制造有限公司 | 2022-08-05 | — | — | CN | claimed |
| EP-3212688-B1 | THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES | LUBRIZOL ADVANCED MAT INC (US) | 2022-04-13 | — | — | EP | claimed |
| US-20220087924-A1 | TWO-DOSAGE-FORM ESSENCE AND PREPARATION METHOD THEREOF | Guangzhou Biohope Co., Ltd. (CN) | 2022-03-24 | — | — | US | claimed |
| WO-2021259544-A2 | PIGMENT SUSPENSION AND COSMETIC AGENT PREPARED USING THE PIGMENT SUSPENSION | HENKEL AG & CO. KGAA (DE) | 2021-12-30 | — | — | WO | claimed |
| WO-2021259543-A1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DERIVATIVE OF ALKYLATED SILANOL, A COLORING COMPOUND AND A POST-TREATMENT AGENT | HENKEL AG & CO. KGAA (DE) | 2021-12-30 | — | — | WO | claimed |
| EP-3881819-A1 | TWO-DOSAGE-FORM ESSENCE AND PREPARATION METHOD THEREFOR | Guangzhou Biohope Co., Ltd. (CN) | 2021-09-22 | — | — | EP | claimed |
| EP-2825047-A1 | PROBIOTIC/ANTIOXIDANT BLEND | Revlon (US) | 2015-01-21 | — | — | EP | claimed |
| WO-2013137899-A1 | PROBIOTIC/ANTIOXIDANT BLEND | REVLON (US) | 2013-09-19 | — | — | WO | claimed |
| EP-1205184-B1 | Methylsilanol hydroxyproline aspartate and palmitoyl-pentapeptide-based synergistic composition | THABAUT SIMON (FR) | 2009-03-11 | — | — | EP | claimed |
| EP-1646359-B1 | PREPARATION FOR TOPICAL USE WITH THE FUNCTION OF COMBATING HAIR LOSS | GECOMWERT ANSTALT (LI) | 2007-04-25 | — | — | EP | claimed |
| EP-1646359-A1 | PREPARATION FOR TOPICAL USE WITH THE FUNCTION OF COMBATING HAIR LOSS | Gecomwert Anstalt (LI) | 2006-04-19 | — | — | EP | claimed |
| US-20060057093-A1 | Preparation for topical use with the function of combating hair loss | GECOMWERT, ANSTALT (LI) | 2006-03-16 | — | — | US | claimed |
| WO-2005007125-A1 | PREPARATION FOR TOPICAL USE WITH THE FUNCTION OF COMBATING HAIR LOSS | GECOMWERT ANSTALT (LI) | 2005-01-27 | — | — | WO | claimed |
| US-20020155962-A1 | Nonaqueous hair styling composition and method of use | ANDREW JERGENS COMPANY, THE | 2002-10-24 | — | — | US | claimed |
| EP-1205184-A1 | Methylsilanol hydroxyproline aspartate-based composition | Thabaut, Simon (FR) | 2002-05-15 | — | — | EP | claimed |
| US-5204105-A | For reducing puffiness, irritation under the eyes; plant and vegetable extracts, silicone, selenium and vitamin components | CHANEL, INC. (US) | 1993-04-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230240963-A1 | PIGMENT SUSPENSION AND COSMETIC AGENT PREPARED USING THE PIGMENT SUSPENSION | RCC1, CCNA1, TYR | GRIK1 4349/4885GRIK2 4481/4885SLC1A2 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.