Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273544 | 0.91 | KDM4E (0.40) | PTGER4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL7425320 | 0.80 | KDM4E (0.38) | GAAKDM4EALDH1A1MAPTTHRB | |
| SCHEMBL19020075 | 0.75 | PTGER4 (0.48) | PTGER4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL23189034 | 0.74 | GAA (0.47) | PTGER4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL5240270 | 0.73 | BRD4 (0.48) | PTGER4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL7429986 | 0.71 | ALOX15 (0.42) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL24619470 | 0.71 | HDAC8 (0.48) | ALDH1A1KDM1AHSD11B1 | |
| SCHEMBL15175798 | 0.70 | PTGER4 (0.46) | PTGER4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL21816632 | 0.70 | CA14 (0.36) | KDM1AHSD11B1 | |
| SCHEMBL27556392 | 0.70 | GCGR (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630823-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-06-14 | — | — | CN | disclosed |