Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757694 | 0.95 | MAPK14 (0.32) | MAPK10MAPK14PDE4APDE4BPDE4D | |
| SCHEMBL27618510 | 0.92 | MAPK14 (0.31) | MAPK10MAPK14PDE4APDE4BPDE4D | |
| SCHEMBL5353665 | 0.76 | MAPK14 (0.43) | MAPK10MAPK14PDE4APDE4BPDE4D | |
| SCHEMBL1957450 | 0.69 | CSNK1D (0.41) | MAPK10MAPK14PDE4APDE4BPDE4D | |
| SCHEMBL5354132 | 0.67 | MAPK14 (0.38) | MAPK10MAPK14PDE4APDE4BPDE4D | |
| SCHEMBL1956243 | 0.64 | CSNK1D (0.40) | MAPK10MAPK14PDE4APDE4BPDE4D | |
| SCHEMBL5348807 | 0.64 | BUB1 (0.38) | MAPK10KCNH2BRAFMAPK3MAPK1 | |
| SCHEMBL5356281 | 0.63 | SMN1; SMN2 (0.38) | MAPK10MAPK14KCNH2BRAFMAPK3 | |
| SCHEMBL5348658 | 0.63 | CSNK1D (0.41) | MAPK10MAPK14PDE4APDE4BPDE4D | |
| SCHEMBL5352280 | 0.62 | PDE3B (0.43) | MAPK14KCNH2BRAFMAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100519552-C | Pyrazole compounds | UBE INDUSTRIES (JP) | 2009-07-29 | — | — | CN | claimed |
| CN-1684953-A | Pyrazole compounds | UBE INDUSTRIES (JP) | 2005-10-19 | — | — | CN | claimed |
| CN-100519552-C | Pyrazole compounds | UBE INDUSTRIES (JP) | 2009-07-29 | — | — | CN | disclosed |
| CN-1684953-A | Pyrazole compounds | UBE INDUSTRIES (JP) | 2005-10-19 | — | — | CN | disclosed |