Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28754668 | 0.95 | MAPK10 (0.31) | MAPK14KCNH2PDE4APDE4BPDE4D | |
| SCHEMBL27618510 | 0.91 | MAPK14 (0.31) | MAPK14KCNH2PDE4APDE4BPDE4D | |
| SCHEMBL5353665 | 0.77 | MAPK14 (0.43) | MAPK14KCNH2PDE4APDE4BPDE4D | |
| SCHEMBL1957450 | 0.70 | CSNK1D (0.41) | MAPK14KCNH2PDE4APDE4BPDE4D | |
| SCHEMBL5354132 | 0.68 | MAPK14 (0.38) | MAPK14KCNH2PDE4APDE4BPDE4D | |
| SCHEMBL1956243 | 0.66 | CSNK1D (0.40) | MAPK14KCNH2PDE4APDE4BPDE4D | |
| SCHEMBL5348807 | 0.65 | BUB1 (0.38) | KCNH2MAPK10CSNK1DCSNK1EROCK2 | |
| SCHEMBL5356281 | 0.65 | SMN1; SMN2 (0.38) | MAPK14KCNH2MAPK10BRAFMAPK3 | |
| SCHEMBL5348658 | 0.64 | CSNK1D (0.41) | MAPK14KCNH2PDE4APDE4BPDE4D | |
| SCHEMBL1650894 | 0.64 | MAPK14 (0.50) | MAPK14PDE4APDE4BMAPK10CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100519552-C | Pyrazole compounds | UBE INDUSTRIES (JP) | 2009-07-29 | — | — | CN | claimed |
| CN-1684953-A | Pyrazole compounds | UBE INDUSTRIES (JP) | 2005-10-19 | — | — | CN | claimed |
| CN-100519552-C | Pyrazole compounds | UBE INDUSTRIES (JP) | 2009-07-29 | — | — | CN | disclosed |
| CN-1684953-A | Pyrazole compounds | UBE INDUSTRIES (JP) | 2005-10-19 | — | — | CN | disclosed |