Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924636 | 0.81 | KDM1A (0.47) | KDM1AMAOBHCAR2TSHRSIGMAR1 | |
| SCHEMBL770184 | 0.79 | KDM1A (0.46) | KDM1AMAOBHCAR2TSHRSIGMAR1 | |
| SCHEMBL3832135 | 0.75 | KDM1A (0.46) | KDM1AMAOBHCAR2TSHRSIGMAR1 | |
| SCHEMBL7351821 | 0.75 | KDM1A (0.46) | KDM1AMAOBHCAR2TSHRSIGMAR1 | |
| SCHEMBL7887551 | 0.75 | KDM1A (0.46) | KDM1AMAOBHCAR2TSHRSIGMAR1 | |
| SCHEMBL11239758 | 0.74 | KDM1A (0.48) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL30657026 | 0.74 | KDM1A (0.48) | KDM1AMAOBHCAR2TSHRSIGMAR1 | |
| SCHEMBL1535911 | 0.74 | KDM1A (0.48) | KDM1AMAOBHCAR2TSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL28824327 | 0.72 | KDM1A (0.47) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL1917700 | 0.72 | KDM1A (0.47) | KDM1AMAOBHCAR2TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100347141-C | Preparation method of 2,3-dichlor-1,4-naphthaquinones | JIANGSU HUADA CHEMICAL GROUP C (CN) | 2007-11-07 | — | — | CN | disclosed |
| CN-1733678-A | Preparation method of 2,3-dichlor-1,4-naphthaquinones | JIANGSU HUADA CHEMICAL GROUP C (CN) | 2006-02-15 | — | — | CN | disclosed |