Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28754736 | 0.81 | KDM1A (0.43) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL1535911 | 0.79 | KDM1A (0.48) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL30657026 | 0.79 | KDM1A (0.48) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL11239758 | 0.79 | KDM1A (0.48) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| Hydrochloric Acid SCHEMBL28824327 | 0.77 | KDM1A (0.47) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL1917700 | 0.77 | KDM1A (0.47) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| Benzene SCHEMBL11415270 | 0.77 | KDM1A (0.47) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL11250762 | 0.76 | KDM1A (0.46) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL770184 | 0.76 | KDM1A (0.46) | KDM1AMAOBTSHRSIGMAR1HDAC9 | |
| SCHEMBL4980269 | 0.76 | KDM1A (0.50) | KDM1AMAOBTSHRSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216283-B | Quinazoline derivatives as NK3 receptor antagonists | HOFFMANN LA ROCHE | 2013-11-27 | — | — | CN | claimed |
| CN-115379856-A | Engineered antibodies to HIV Env | 国际艾滋病疫苗行动组织 | 2022-11-22 | — | — | CN | disclosed |
| US-10300062-B2 | Bicyclically substituted uracils and the use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-05-28 | — | — | US | disclosed |
| US-20180256576-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-09-13 | — | — | US | disclosed |
| CN-108059607-A | Sulfoxide guanidine-acetic acid or sulfuryl phenylacetic acid derivative, its pharmaceutical composition, preparation method and purposes | 中国科学院上海药物研究所 | 2018-05-22 | — | — | CN | disclosed |
| US-9949977-B2 | Bicyclically substituted uracils and the use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20170020876-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | US | disclosed |
| CN-105358586-A | Cyclopropyl substituted metallocene catalysts | EXXONMOBIL CHEM PATENTS INC | 2016-02-24 | — | — | CN | disclosed |
| CN-102216283-B | Quinazoline derivatives as NK3 receptor antagonists | HOFFMANN LA ROCHE | 2013-11-27 | — | — | CN | disclosed |
| US-5605819-A | USING BROMIDE ION AND HYDROGEN PEROXIDE | MERCK & CO., INC. (US) | 1997-02-25 | — | — | US | disclosed |
| WO-1996036724-A1 | QUANTITATIVE CONVERSION OF INDENE TO (1S,2R) INDENE OXIDE AND (1S,2R)-INDANDIOL BY COMBINATION OF HALOPEROXIDASE BIOCONVERSION AND CHEMICAL STEPS | MERCK & CO., INC. (US) | 1996-11-21 | — | — | WO | disclosed |
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170020876-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | UNG, UMPS, TYMP | KDM1A 3789/4885MAOB 280/4885TSHR 4588/4885 |
| US-10300062-B2 | Bicyclically substituted uracils and the use thereof | UNG, UMPS, TYMP | KDM1A 3789/4885MAOB 280/4885TSHR 4588/4885 |
| US-20180256576-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | UNG, UMPS, TYMP | KDM1A 3789/4885MAOB 280/4885TSHR 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.