Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.52 |
| ▸ | CES1 | P23141 | 7/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877201 | 0.87 | TSHR (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL30525458 | 0.84 | FAAH (0.55) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL6703244 | 0.84 | FAAH (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL5658044 | 0.84 | FAAH (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL6703335 | 0.84 | FAAH (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9755221 | 0.84 | FAAH (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL2127229 | 0.82 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28995677 | 0.82 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL17003745 | 0.79 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9055251 | 0.79 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046148-B1 | ORGANIC COMPOUNDS AND METHODS | GIVAUDAN SA (CH) | 2010-10-20 | — | — | EP | disclosed |