Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755192 | 0.88 | GAA (0.60) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28605562 | 0.87 | NPC1 (0.59) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28605559 | 0.87 | NPC1 (0.59) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28755330 | 0.85 | GAA (0.56) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28755189 | 0.85 | GAA (0.56) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL12692456 | 0.84 | MAPT (0.67) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28755329 | 0.83 | KMT2A (0.60) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28755342 | 0.83 | GAA (0.53) | GAARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28755308 | 0.82 | GAA (0.53) | GAARAB9AMAPTNPC1HTT | |
| SCHEMBL28755281 | 0.81 | GAA (0.51) | GAARAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382899-B | Polysubstituted 2-hydroxy-1, 4-benzoxazine derivative | 华侨大学 | 2021-11-30 | — | — | CN | disclosed |