Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755192 | 0.86 | GAA (0.60) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28942168 | 0.82 | GAA (0.54) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28755189 | 0.81 | GAA (0.56) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28755330 | 0.81 | GAA (0.56) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28755342 | 0.81 | GAA (0.53) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28755329 | 0.81 | KMT2A (0.60) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28755304 | 0.81 | GAA (0.56) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28755308 | 0.78 | GAA (0.53) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28755238 | 0.78 | GAA (0.50) | GAAMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6627530 | 0.77 | NPC1 (0.69) | GAAKDM4EKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382899-B | Polysubstituted 2-hydroxy-1, 4-benzoxazine derivative | 华侨大学 | 2021-11-30 | — | — | CN | disclosed |