SCHEMBL287555

SCHEMBL287555

CC(C)OC(=O)C1=CN=CC(CC(=O)c2ccccc2)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.36
F2 P00734 1/20 0.36
PLAU P00749 1/20 0.36
ELANE P08246 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
SCN1A P35498 1/20 0.34
SCN2A Q99250 1/20 0.34
SCN3A Q9NY46 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid 1-Methylethyl Ester SCHEMBL96918 0.66 PDCD1 (0.78) PDCD1CD274NPC1RAB9AHTT
Benzoic Acid 1-Methylethyl Ester SCHEMBL27592410 0.66 PDCD1 (0.78) PDCD1CD274NPC1RAB9AHTT
Benzoic Acid 1-Methylethyl Ester SCHEMBL29019189 0.64 PDCD1 (0.75) PDCD1CD274NPC1RAB9AHTT
Benzoic Acid 1-Methylethyl Ester SCHEMBL8381956 0.64 PDCD1 (0.75) PDCD1CD274NPC1RAB9AHTT
Benzoic Acid 1-Methylethyl Ester SCHEMBL9343935 0.64 PDCD1 (0.75) PDCD1CD274NPC1RAB9AHTT
Benzoic Acid 1-Methylethyl Ester SCHEMBL31017505 0.64 PDCD1 (0.75) PDCD1CD274NPC1RAB9AHTT
Benzoic Acid 1-Methylethyl Ester SCHEMBL28432759 0.64 PDCD1 (0.75) PDCD1CD274NPC1RAB9AHTT
SCHEMBL660364 0.63 PDCD1 (0.43) PDCD1CD274NPC1RAB9AHTT
SCHEMBL1200654 0.62 TSHR (0.58) PDCD1CD274NPC1RAB9AHTT
Benzoic Acid 1-Methylethyl Ester SCHEMBL29187646 0.62 PDCD1 (0.70) PDCD1CD274NPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427432-A2 NOVEL HETEROCYCLIC COMPOUNDS Torrent Pharmaceuticals Limited (IN) 2012-03-14 EP disclosed
WO-2010128528-A2 NOVEL HETEROCYCLIC COMPOUNDS TORRENT PHARMACEUTICALS LIMITED (IN) 2010-11-11 WO disclosed