Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658507 | 0.86 | TSHR (0.42) | NPC1HTTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL27854995 | 0.82 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL660962 | 0.81 | KMT2A (0.41) | NPC1HTTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL660917 | 0.80 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL298474 | 0.78 | SMN1; SMN2 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27871677 | 0.77 | ALDH1A1 (0.38) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL660154 | 0.77 | SMN1; SMN2 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7805087 | 0.77 | HDAC1 (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27854950 | 0.74 | ADRA2C (0.35) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL287206 | 0.73 | PTGS2 (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | PDCD1 4410/4885CD274 4532/4885NPC1 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.