Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643121 | 0.89 | HTR6 (0.53) | HTR6DRD2HTR1AHTR2A | |
| SCHEMBL27750199 | 0.83 | HTR6 (0.56) | HTR6 | |
| SCHEMBL27623636 | 0.81 | HTR6 (0.55) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL27771343 | 0.79 | HDAC3 (0.35) | HTR6 | |
| SCHEMBL4321340 | 0.79 | HTR6 (0.80) | HTR6DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL4314129 | 0.78 | HTR6 (0.78) | HTR6DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL27643115 | 0.76 | HTR6 (0.48) | HTR6DRD2HTR1AHTR2A | |
| SCHEMBL28755537 | 0.74 | HTR6 (0.53) | HTR6DRD2HTR1AHTR2A | |
| SCHEMBL27771240 | 0.74 | HTR6 (0.56) | HTR6 | |
| SCHEMBL27771251 | 0.74 | HTR6 (0.47) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101298433-A | 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy | BIOVITRUM AB (SE) | 2008-11-05 | — | — | CN | disclosed |
| CN-100378074-C | 2-, 3-, 4-or 5-substituted N1- (phenylsulfonyl) indoles and their therapeutic use | BIOVITRUM AB (SE) | 2008-04-02 | — | — | CN | disclosed |
| CN-1714077-A | 2-, 3-, 4-or 5-substituted N1- (phenylsulfonyl) indoles and their therapeutic use | BIOVITRUM AB (SE) | 2005-12-28 | — | — | CN | disclosed |