Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689862 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL6637777 | 0.84 | MAPK14 (0.48) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL4951785 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL4943890 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL19060480 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL6298784 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL19037746 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL1599772 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL19022324 | 0.80 | MEN1 (0.43) | ALDH1A1TSHRTDP1HTTNPC1 | |
| SCHEMBL16106362 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717162-A | Urea derivatives as kinase inhibitors | 奥苏拉收购有限公司 | 2021-11-30 | — | — | CN | disclosed |