Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | F3 | P13726 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31252801 | 0.83 | CHRNA7 (0.50) | ABCG2CYP1B1P4HBCHRNA7 | |
| SCHEMBL3340539 | 0.83 | DPP4 (0.46) | MAPTLY96XDH | |
| SCHEMBL3340551 | 0.83 | DPP4 (0.46) | MAPTLY96XDH | |
| SCHEMBL365871 | 0.79 | MAOA (0.53) | MAPTRAB9AMAOBMAOANPC1 | |
| SCHEMBL1390404 | 0.79 | MAOA (0.53) | MAPTRAB9AMAOBMAOANPC1 | |
| SCHEMBL28714547 | 0.77 | MAPT (0.54) | MAPTRAB9AMAOBMAOANPC1 | |
| SCHEMBL1124221 | 0.76 | KDM4E (0.48) | MAPTNPC1LY96KDM4ESMN1; SMN2 | |
| SCHEMBL4574402 | 0.76 | KDM4E (0.44) | MAPTLMNALY96KDM4ESMN1; SMN2 | |
| SCHEMBL4574403 | 0.76 | KDM4E (0.44) | MAPTLMNALY96KDM4ESMN1; SMN2 | |
| SCHEMBL28497749 | 0.73 | JAK2 (0.56) | MAPTRAB9AMAOBMAOAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293616-B | Coumarin-containing chalcone derivatives, and preparation method and application thereof | 贵州大学 | 2022-06-21 | — | — | CN | disclosed |