SCHEMBL28756563

SCHEMBL28756563

CCCCCC1(C=O)CCCC1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
SIRT2 Q8IXJ6 1/20 0.34
ADH1C P00326 2/20 0.33
ADH1A P07327 2/20 0.33
ADH4 P08319 2/20 0.33
EPHX1 P07099 1/20 0.33
ADH1B P00325 1/20 0.33
ADH7 P40394 1/20 0.33
FAAH O00519 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
CETP P11597 3/20 0.32
PTPN1 P18031 1/20 0.31
ACP1 P24666 1/20 0.31
CDC25B P30305 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2236262 0.98 TSHR (0.34) TSHRSIRT2ADH1CADH1AADH4
SCHEMBL11503129 0.96 TSHR (0.38) TSHRSIRT2ADH1CADH1AADH4
SCHEMBL9646862 0.96 TSHR (0.38) TSHRSIRT2ADH1CADH1AADH4
SCHEMBL22098328 0.95 TSHR (0.36) TSHRSIRT2ADH1CADH1AADH4
SCHEMBL31076221 0.93 TSHR (0.35) TSHRADH1CADH1AADH4EPHX1
SCHEMBL9173367 0.91 CETP (0.33) TSHRADH1CADH1AADH1BADH7
SCHEMBL3193317 0.91 TSHR (0.39) TSHRSIRT2ADH1CADH1AADH4
SCHEMBL1326477 0.88 TSHR (0.35) TSHRADH1CADH1AADH4EPHX1
SCHEMBL3963526 0.88 TSHR (0.42) TSHRSIRT2ADH1CADH1AADH4
SCHEMBL3181124 0.88 TSHR (0.42) TSHRSIRT2ADH1CADH1AADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478217-A Preparation method of 2-n-pentylcyclopent-2-enone 山东新和成药业有限公司 2022-05-13 CN disclosed