Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503129 | 0.98 | TSHR (0.38) | TSHRCETPSIRT2EPHX1ADH1B | |
| SCHEMBL9646862 | 0.98 | TSHR (0.38) | TSHRCETPSIRT2EPHX1ADH1B | |
| SCHEMBL28756563 | 0.98 | TSHR (0.36) | TSHRCETPSIRT2EPHX1ADH1B | |
| SCHEMBL9173367 | 0.93 | CETP (0.33) | TSHRCETPADH1BADH1CADH1A | |
| SCHEMBL22098328 | 0.93 | TSHR (0.36) | TSHRSIRT2EPHX1ADH1BADH1C | |
| SCHEMBL31076221 | 0.91 | TSHR (0.35) | TSHRCETPEPHX1ADH1BADH1C | |
| SCHEMBL3193317 | 0.89 | TSHR (0.39) | TSHRSIRT2EPHX1ADH1BADH1C | |
| SCHEMBL3188358 | 0.86 | TSHR (0.42) | TSHRSIRT2EPHX1ADH1BADH1C | |
| SCHEMBL1326477 | 0.86 | TSHR (0.35) | TSHREPHX1ADH1BADH1CADH1A | |
| SCHEMBL3181124 | 0.86 | TSHR (0.42) | TSHRSIRT2EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108603960-A | Method of manufacturing optical articles with ink jet printing apparatus | 光学转变有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108351451-A | Optical article having gradient light influencing properties and method of making same | 光学转变公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108349177-A | Method of making an optical article having gradient light influencing properties | 光学转变公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108351446-A | Optical article and method of making the same | 光学转变公司 | 2018-07-31 | — | — | CN | disclosed |
| EP-2528907-A1 | THERAPEUTICALLY ACTIVE CYCLOPENTANES | Allergan, Inc. (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8299068-B2 | Therapeutically active cyclopentanes | ALLERGAN, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299068-B2 | Therapeutically active cyclopentanes | ALLERGAN, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299068-B2 | Therapeutically active cyclopentanes | ALLERGAN, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| WO-2011094225-A1 | THERAPEUTICALLY ACTIVE CYCLOPENTANES | ALLERGAN, INC. (US) | 2011-08-04 | — | — | WO | disclosed |
| WO-2011094225-A1 | THERAPEUTICALLY ACTIVE CYCLOPENTANES | ALLERGAN, INC. (US) | 2011-08-04 | — | — | WO | disclosed |
| US-20110190286-A1 | THERAPEUTICALLY ACTIVE CYCLOPENTANES | ALLERGAN, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110190286-A1 | THERAPEUTICALLY ACTIVE CYCLOPENTANES | ALLERGAN, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110190286-A1 | THERAPEUTICALLY ACTIVE CYCLOPENTANES | ALLERGAN, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190286-A1 | THERAPEUTICALLY ACTIVE CYCLOPENTANES | TUBB6, ANXA5, TUBB1 | TSHR 4009/4885CETP 264/4885SIRT2 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.