Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878332 | 0.92 | TAAR1 (0.46) | TAAR1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3595204 | 0.84 | CYP3A4 (0.36) | KMT2AMEN1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2009715 | 0.84 | CYP3A4 (0.36) | KMT2AMEN1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2875735 | 0.81 | ABCC9 (0.33) | KDM4ECYP3A4CYP2C19HIF1AABCC9 | |
| SCHEMBL2875833 | 0.79 | ABCC9 (0.37) | KDM4ECYP3A4CYP2C19HIF1AABCC9 | |
| SCHEMBL2875832 | 0.79 | ABCC9 (0.37) | KDM4ECYP3A4CYP2C19HIF1AABCC9 | |
| SCHEMBL12580755 | 0.77 | GRM2 (0.36) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2008357 | 0.76 | ABCC9 (0.39) | KMT2AMEN1KDM4ELMNACYP3A4 | |
| SCHEMBL2878901 | 0.76 | ABCC9 (0.39) | KMT2AMEN1KDM4ELMNACYP3A4 | |
| SCHEMBL2887474 | 0.75 | KDM4E (0.36) | TAAR1ALDH1A1KDM4ECYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732929-B1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2010-10-20 | — | — | EP | disclosed |