Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPRC | P08575 | 3/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477072 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4TSHRPTPRC | |
| SCHEMBL16979609 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP3A4TSHRACHE | |
| SCHEMBL27527076 | 0.82 | TDP1 (0.51) | ALDH1A1TDP1CYP3A4TSHRERN1 | |
| SCHEMBL4322153 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRERN1 | |
| SCHEMBL16960664 | 0.80 | TDP1 (0.44) | ALDH1A1TDP1CYP3A4TSHRPTPRC | |
| SCHEMBL29607775 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4TSHRPTPRC | |
| SCHEMBL22866211 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4TSHRPTPRC | |
| SCHEMBL27787684 | 0.77 | HSD17B10 (0.53) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL28757447 | 0.77 | GAA (0.44) | ALDH1A1TDP1CYP3A4TSHRPTPRC | |
| SCHEMBL18048536 | 0.76 | PTPRC (0.44) | ALDH1A1TDP1CYP3A4TSHRPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1829709-A | Bicyclic imidazol derivatives against flaviviridae | GENELABS TECH INC (US) | 2006-09-06 | — | — | CN | disclosed |