Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23802307 | 0.83 | SLC6A2 (0.47) | CYP2D6CYP19A1MEN1KMT2ACHRM2 | |
| SCHEMBL2264957 | 0.82 | CHRM2 (0.56) | CYP2D6CYP19A1MEN1KMT2ACHRM2 | |
| SCHEMBL2390369 | 0.82 | CHRM2 (0.56) | CYP2D6CYP19A1MEN1KMT2ACHRM2 | |
| SCHEMBL17460117 | 0.82 | MEN1 (0.61) | CYP2D6MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL2264950 | 0.82 | CHRM2 (0.56) | CYP2D6CYP19A1MEN1KMT2ACHRM2 | |
| SCHEMBL15100999 | 0.78 | CYP2D6 (0.67) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL11624726 | 0.78 | CHRM2 (0.52) | CYP2D6CYP19A1MEN1KMT2ACHRM2 | |
| SCHEMBL27789355 | 0.76 | CHRNB2 (0.36) | MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL24556564 | 0.75 | CYP2D6 (0.44) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL27845132 | 0.75 | CYP2D6 (0.44) | CYP2D6CYP19A1MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1703393-A | Spiro compounds, medicinal compositions containing the same and intermediates of the compounds | DAINIPPON PHARMACEUTICAL CO (JP) | 2005-11-30 | — | — | CN | disclosed |