SCHEMBL28758233

SCHEMBL28758233

CCOC(CSc1ccc(O)c(C)c1)CC(OCC)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.51
PPARA Q07869 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377858 0.84 PPARD (0.74) PPARDPPARA
SCHEMBL7019616 0.82 PPARD (0.72) PPARDPPARA
SCHEMBL7018405 0.75 PPARD (0.57) PPARDPPARA
SCHEMBL7017818 0.74 PPARD (0.73) PPARDPPARA
SCHEMBL7018183 0.74 PPARD (0.73) PPARDPPARA
SCHEMBL377973 0.74 PPARD (0.73) PPARDPPARA
SCHEMBL7017697 0.73 PPARD (0.74) PPARDPPARA
SCHEMBL7019523 0.73 PPARD (0.71) PPARDPPARA
SCHEMBL5404604 0.72 PPARD (0.60) PPARDPPARA
SCHEMBL7020224 0.72 PPARD (0.61) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1882533-A 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs JANSSEN PHARMACEUTICA NV (BE) 2006-12-20 CN claimed
CN-1882533-B 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs JANSSEN PHARMACEUTICA NV 2010-06-09 CN disclosed
CN-1882533-A 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs JANSSEN PHARMACEUTICA NV (BE) 2006-12-20 CN disclosed