Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 5/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656294 | 0.86 | CYP4A11 (0.54) | BRS3CNR1CNR2ESRRGCYP4A11 | |
| SCHEMBL21629639 | 0.85 | BRS3 (0.53) | BRS3CNR1CNR2ESRRGCYP4A11 | |
| SCHEMBL23583035 | 0.83 | NR1H4 (0.54) | BRS3NR1H4EPHX2L3MBTL1LMNA | |
| SCHEMBL24172240 | 0.83 | CYP4A11 (0.57) | BRS3CNR1CNR2ESRRGCYP4A11 | |
| SCHEMBL8584934 | 0.83 | PLK1 (0.53) | BRS3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8974321 | 0.83 | CNR1 (0.54) | BRS3CNR1CNR2KCNN4MEN1 | |
| SCHEMBL8860658 | 0.83 | BRS3 (0.49) | BRS3CNR1CNR2ESRRGCYP4A11 | |
| SCHEMBL5642443 | 0.82 | BRS3 (0.50) | BRS3CNR1CNR2CYP4A11CYP4F2 | |
| SCHEMBL2601862 | 0.82 | BRS3 (0.50) | BRS3CNR1CNR2KCNN4RORC | |
| SCHEMBL24171971 | 0.82 | CYP4A11 (0.58) | BRS3CNR1CNR2ESRRGCYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591291-B | Bilastine intermediate compound and preparation method thereof | 鲁南制药集团股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-114591292-B | Bilastine intermediate compounds | 鲁南制药集团股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-115745954-A | Preparation method of bilastine intermediate | 山东新时代药业有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-114591291-A | Bilastine intermediate compound and preparation method thereof | 鲁南制药集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591292-A | Bilastine intermediate compound | 鲁南制药集团股份有限公司 | 2022-06-07 | — | — | CN | disclosed |