Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 7/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 6/20 | 0.54 |
| ▸ | BRS3 | P32247 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ESRRG | P62508 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24172240 | 0.90 | CYP4A11 (0.57) | CYP4A11CYP4F2BRS3PPARACNR1 | |
| SCHEMBL24171971 | 0.89 | CYP4A11 (0.58) | CYP4A11CYP4F2BRS3PPARACNR1 | |
| SCHEMBL28758271 | 0.86 | BRS3 (0.54) | CYP4A11CYP4F2BRS3CNR1CNR2 | |
| SCHEMBL5642443 | 0.86 | BRS3 (0.50) | CYP4A11CYP4F2BRS3PPARACNR1 | |
| SCHEMBL27796483 | 0.85 | BRS3 (0.53) | CYP4A11CYP4F2BRS3CNR1CNR2 | |
| SCHEMBL21629639 | 0.85 | BRS3 (0.53) | CYP4A11CYP4F2BRS3CNR1CNR2 | |
| SCHEMBL23583035 | 0.83 | NR1H4 (0.54) | BRS3PPARAALDH1A1 | |
| SCHEMBL8584934 | 0.83 | PLK1 (0.53) | BRS3ALDH1A1POLB | |
| SCHEMBL992232 | 0.83 | CYP4F2 (0.57) | CYP4A11CYP4F2BRS3PPARACNR2 | |
| SCHEMBL8974321 | 0.83 | CNR1 (0.54) | BRS3CNR1CNR2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129039-A1 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2025-04-24 | — | — | US | disclosed |
| WO-2023037184-A2 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2023-03-16 | — | — | WO | disclosed |
| CN-110698343-B | Synthesis method of bilastine intermediate | 荆门医药工业技术研究院 | 2022-04-01 | — | — | CN | disclosed |
| CN-110698343-B | Synthesis method of bilastine intermediate | 荆门医药工业技术研究院 | 2022-04-01 | — | — | CN | disclosed |
| CN-113979960-B | Preparation method of bilastine intermediate | 南京桦冠生物技术有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113979960-A | Preparation method of bilastine intermediate | 南京桦冠生物技术有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-107365297-B | Preparation method and intermediate of 2-methyl-2' -phenylpropionic acid derivative | 罗欣药业(上海)有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-110698343-A | Synthesis method of bilastine intermediate | 荆门医药工业技术研究院 | 2020-01-17 | — | — | CN | disclosed |
| CN-110698343-A | Synthesis method of bilastine intermediate | 荆门医药工业技术研究院 | 2020-01-17 | — | — | CN | disclosed |
| CN-104402773-A | Process for the preparation of 2-methyl-2' -phenylpropionic acid derivatives and intermediate compounds | YUHAN CORP | 2015-03-11 | — | — | CN | disclosed |
| US-20130116439-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2013-05-09 | — | — | US | disclosed |
| US-7863452-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| EP-2240464-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | Yuhan Corporation (KR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009102155-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2009-08-20 | — | — | WO | disclosed |
| US-20090124810-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-7176318-B2 | Processes for the production of fexofenadine | TEXCONTOR ESTABLISSEMENT (LI) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124810-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | HADHB, CPT1B, PDHB | CYP4A11 1616/4885CYP4F2 603/4885BRS3 1311/4885 |
| US-20130116439-A1 | PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH2, HRH4, HNMT | CYP4A11 232/4885CYP4F2 750/4885BRS3 1384/4885 |
| US-20250129039-A1 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | CYP4B1, CYP3A4, CYP7A1 | CYP4A11 16/4885CYP4F2 64/4885BRS3 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.