Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | VDR | P11473 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18382514 | 0.86 | CYP19A1 (0.53) | CYP19A1MCL1VDRF2F10 | |
| SCHEMBL25930735 | 0.82 | MCL1 (0.47) | CYP19A1MCL1VDRF2F10 | |
| SCHEMBL13957035 | 0.82 | CYP19A1 (0.86) | CYP19A1P2RX4HDAC6HDAC1HDAC10 | |
| SCHEMBL17468682 | 0.81 | MCL1 (0.44) | CYP19A1MCL1VDRF2F10 | |
| SCHEMBL14849331 | 0.81 | CYP19A1 (0.64) | CYP19A1P2RX4HDAC6HDAC1HDAC10 | |
| SCHEMBL9128630 | 0.80 | CYP19A1 (0.76) | CYP19A1KMT2AP2RX4HDAC6HDAC1 | |
| SCHEMBL19669322 | 0.80 | MCL1 (0.43) | CYP19A1MCL1VDRF2F10 | |
| SCHEMBL26214830 | 0.80 | MCL1 (0.48) | CYP19A1MCL1VDRF2F10 | |
| SCHEMBL16186874 | 0.79 | CYP19A1 (0.72) | CYP19A1KMT2AP2RX4HDAC6HDAC1 | |
| SCHEMBL25930681 | 0.78 | CYP1A2 (0.47) | CYP19A1MCL1VDRF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100412060-C | Prepn of-2-(N-carbazolyl)-ethoxy carbohydrazide | DALIAN CHEMICAL PHYSICS INST (CN) | 2008-08-20 | — | — | CN | disclosed |
| CN-1810789-A | Prepn of-2-(N-carbazolyl)-ethoxy carbohydrazide | DALIAN CHEMICAL PHYSICS INST (CN) | 2006-08-02 | — | — | CN | disclosed |