SCHEMBL17468682

SCHEMBL17468682

Oc1ccccc1-c1ccc2c(c1)c1ccccc1n2Cc1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.44
F10 P00742 5/20 0.43
F2 P00734 4/20 0.43
PRSS1 P07477 4/20 0.43
ESR2 Q92731 1/20 0.43
ICMT O60725 2/20 0.42
CYP19A1 P11511 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.40
VDR P11473 1/20 0.40
SRC P12931 1/20 0.40
SLC5A1 P13866 1/20 0.39
SLC5A2 P31639 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSPO P30536 1/20 0.38
HDAC6 Q9UBN7 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28758680 0.81 CYP19A1 (0.60) MCL1F10F2PRSS1CYP19A1
SCHEMBL18382514 0.76 CYP19A1 (0.53) MCL1F10F2PRSS1CYP19A1
SCHEMBL1250807 0.74 PTGER4 (0.51) MCL1F10F2PRSS1PTGDR2
SCHEMBL30463004 0.72 ESR2 (0.78) ESR2ALDH1A1
SCHEMBL217638 0.72 ESR2 (0.78) ESR2ALDH1A1
SCHEMBL27863119 0.70 ESR1 (0.56) ESR2
SCHEMBL17125667 0.70 CYP19A1 (0.62) CYP19A1SRCKDM4EMEN1ALDH1A1
SCHEMBL17759371 0.69 HSD17B1 (0.40) MCL1ESR2KDM4EMEN1ALDH1A1
SCHEMBL27653124 0.69 METAP2 (0.47) ESR2KDM4EMEN1ALDH1A1MAPT
SCHEMBL16848586 0.68 CYP19A1 (0.70) CYP19A1SRCKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016013867-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-01-28 WO disclosed