Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943375 | 0.79 | NPC1 (0.49) | GCKNPC1RAB9AERCC5FEN1 | |
| SCHEMBL4943383 | 0.79 | GCK (0.44) | GCKNPC1RAB9AERCC5FEN1 | |
| SCHEMBL9254905 | 0.77 | NPC1 (0.46) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30147517 | 0.75 | NPC1 (0.60) | GCKNPC1RAB9AMRGPRX4AKR1C3 | |
| SCHEMBL27639502 | 0.75 | RXFP1 (0.51) | NPC1RAB9AL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28043985 | 0.74 | AKR1C3 (0.73) | GCKNPC1RAB9AMRGPRX4PPARG | |
| SCHEMBL30147687 | 0.74 | AKR1C3 (0.73) | GCKNPC1RAB9AMRGPRX4PPARG | |
| SCHEMBL27776094 | 0.74 | NPC1 (0.48) | NPC1RAB9AL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL27660193 | 0.73 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL27660190 | 0.73 | KAT6A (0.43) | NPC1RAB9AMRGPRX4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735597-A | 2-piperidone derivatives as prostaglandin agonists | HOFFMANN LA ROCHE (CH) | 2006-02-15 | — | — | CN | disclosed |