Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28759064 | 0.85 | FFAR4 (0.50) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL22918245 | 0.83 | PTGER1 (0.50) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL29592409 | 0.76 | FFAR1 (0.54) | FFAR1FFAR4CFDNPC1MRGPRX4 | |
| SCHEMBL4840328 | 0.76 | FFAR1 (0.54) | FFAR1FFAR4CFDNPC1MRGPRX4 | |
| SCHEMBL4419617 | 0.75 | KDM1A (0.52) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL3954112 | 0.74 | S1PR5 (0.60) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL29510818 | 0.74 | S1PR5 (0.60) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL21043378 | 0.74 | FFAR4 (0.47) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL3799950 | 0.73 | RXRB (0.49) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL2395263 | 0.73 | PTGER1 (0.56) | FFAR1FFAR4PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616226-A | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2022-06-10 | — | — | CN | disclosed |