Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577467 | 0.85 | GPR119 (0.53) | GPR119PRMT5HPGDS | |
| SCHEMBL3342643 | 0.84 | GPR119 (0.57) | GPR119 | |
| SCHEMBL25169929 | 0.81 | GPR119 (0.50) | GPR119PRMT5HPGDS | |
| SCHEMBL30376767 | 0.81 | GPR119 (0.50) | GPR119PRMT5HPGDS | |
| SCHEMBL1577715 | 0.79 | GPR119 (0.52) | GPR119 | |
| SCHEMBL1556569 | 0.79 | GPR119 (0.48) | GPR119PRMT5 | |
| SCHEMBL28673691 | 0.78 | GPR119 (0.49) | GPR119 | |
| SCHEMBL30378233 | 0.78 | GPR119 (0.47) | GPR119PRMT5 | |
| SCHEMBL11311051 | 0.78 | STS (0.49) | GPR119 | |
| SCHEMBL3060853 | 0.78 | GPR119 (0.48) | GPR119HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621230-B | Nitrogen-containing heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-114621230-A | Nitrogen-containing heterocyclic compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-06-14 | — | — | CN | disclosed |