Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28761900

N.O=C(O)Cc1cccc(Cl)c1

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.64
HTR3E A5X5Y0 1/20 0.56
HTR3B O95264 1/20 0.56
HTR3A P46098 1/20 0.56
HTR3D Q70Z44 1/20 0.56
HTR3C Q8WXA8 1/20 0.56
AKR1B1 P15121 2/20 0.56
PIK3CA P42336 1/20 0.54
ALDH1A1 P00352 4/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HPGD P15428 1/20 0.53
CA2 P00918 1/20 0.52
EPHX2 P34913 1/20 0.51
LMNA P02545 1/20 0.51
PNMT P11086 1/20 0.50
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
RXRG P48443 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL5702482 1.00 CTBP2 (0.64) CTBP2HTR3EHTR3BHTR3AHTR3D
SCHEMBL467923 0.98 CTBP2 (0.66) CTBP2HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL2531827 0.96 CTBP2 (0.64) CTBP2HTR3EHTR3BHTR3AHTR3D
SCHEMBL11774837 0.91 CTBP2 (0.58) CTBP2HTR3EHTR3BHTR3AHTR3D
Parachlorophenol SCHEMBL9108351 0.88 CTBP2 (0.55) CTBP2HTR3EHTR3BHTR3AHTR3D
SCHEMBL4208044 0.87 GRIN2D (0.55) CTBP2AKR1B1CA2LMNA
3-Chloroaniline SCHEMBL11667901 0.84 ALDH1A1 (0.57) CTBP2HTR3EHTR3BHTR3AHTR3D
P-Cresol SCHEMBL9107906 0.84 CTBP2 (0.51) CTBP2HTR3EHTR3BHTR3AHTR3D
SCHEMBL11172110 0.83 CTBP2 (0.62) CTBP2HTR3EHTR3BHTR3AHTR3D
SCHEMBL27834585 0.83 CTBP2 (0.58) CTBP2HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1906203-A Glycosaminoglycan (GAG) mimetics PROGEN IND LTD (AU) 2007-01-31 CN disclosed