Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537497 | 0.85 | S1PR1 (0.36) | S1PR1S1PR5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL6889133 | 0.82 | EDNRB (0.32) | — | |
| SCHEMBL14812065 | 0.81 | S1PR1 (0.35) | S1PR1S1PR5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL28024189 | 0.81 | S1PR1 (0.43) | S1PR1S1PR5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL27463750 | 0.80 | PTGS2 (0.33) | PTGS2SMN1; SMN2KMT2AHPGD | |
| SCHEMBL27512779 | 0.80 | SPHK1 (0.36) | S1PR1S1PR5PTGS2 | |
| SCHEMBL3163967 | 0.80 | BRD4 (0.33) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28761996 | 0.80 | S1PR1 (0.44) | S1PR1S1PR5PTGS2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6375156 | 0.80 | S1PR1 (0.42) | S1PR1S1PR5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL7199373 | 0.79 | HTR2C (0.34) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | claimed |
| CN-1946748-A | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-04-11 | — | — | CN | claimed |
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | disclosed |
| CN-1946748-A | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-04-11 | — | — | CN | disclosed |