Azelaic Acid

Azelaic Acid

SCHEMBL2876285

O=C(O)CCCCCCCC(=O)O.[NaH]

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.92
LMNA P02545 3/20 0.92
NFKB1 P19838 1/20 0.92
PMP22 Q01453 1/20 0.92
SLC22A6 Q4U2R8 2/20 0.71
GPR84 Q9NQS5 8/20 0.71
FFAR1 O14842 2/20 0.71
FFAR4 Q5NUL3 2/20 0.71
PPARG P37231 7/20 0.67
PPARD Q03181 7/20 0.67
PPARA Q07869 7/20 0.67
HDAC11 Q96DB2 5/20 0.67
ALDH1A1 P00352 3/20 0.67
PTPN1 P18031 3/20 0.67
TLR2 O60603 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
MEN1 O00255 2/20 0.67
FABP4 P15090 2/20 0.67
ALOX15 P16050 2/20 0.67
KMT2A Q03164 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL306521 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Pimelic Acid SCHEMBL6756766 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL8638409 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Octanedioate SCHEMBL13732041 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Azelaic Acid SCHEMBL852025 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Octanedioate SCHEMBL188029 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL8028939 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL11046983 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL6053549 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL28971884 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117004136-A Preparation method and application of low-temperature-resistant irradiation-resistant high-transparency medical polypropylene 中广核俊尔(浙江)新材料有限公司 2023-11-07 CN claimed
CN-117004138-A Ionizing radiation-resistant sterilizing low-temperature-resistant high-transparency medical PP (Polypropylene) and preparation method thereof 中广核俊尔(浙江)新材料有限公司 2023-11-07 CN claimed
CN-117004137-A Medical polypropylene for low-temperature centrifuge tube and irradiation resistance and preparation method thereof 中广核俊尔(浙江)新材料有限公司 2023-11-07 CN claimed
CN-115716363-A High-temperature-resistant polyester film and preparation method thereof 合肥乐凯科技产业有限公司 2023-02-28 CN claimed
CN-110628130-B Low-shrinkage polypropylene material suitable for 3D printing and preparation method thereof 东华能源(宁波)新材料有限公司 2022-07-08 CN claimed
CN-112080251-B Wafer grinding fluid and preparation method thereof 威科赛乐微电子股份有限公司 2022-06-10 CN claimed
CN-112795418-A Tetra-urea lubricating grease composition prepared from aromatic diamine and preparation method thereof 青岛中科润美润滑材料技术有限公司 2021-05-14 CN claimed
CN-112375607-A Tetraurea lubricating grease composition and preparation method thereof 青岛中科润美润滑材料技术有限公司 2021-02-19 CN claimed
CN-109183116-B Preparation of a catalyst containing TiO2Pretreatment process of dielectric layer electronic aluminum foil 南通海星电子股份有限公司 2020-07-17 CN claimed
CN-110628130-A Low-shrinkage polypropylene material suitable for 3D printing and preparation method thereof 东华能源(宁波)新材料有限公司 2019-12-31 CN claimed
EP-2965625-A1 PLANT PATHOGEN RESISTANCE The University of Chicago (US) 2016-01-13 EP claimed
US-9161533-B2 Plant pathogen resistance THE UNIVERSITY OF CHICAGO (US) 2015-10-20 US claimed
EP-2187736-B1 PLANT PATHOGEN RESISTANCE UNIV CHICAGO (US) 2015-07-29 EP claimed
US-20130130907-A1 PLANT PATHOGEN RESISTANCE UT-Batlelle, LLC (US) 2013-05-23 US claimed
US-8318786-B2 Plant pathogen resistance THE UNIVERSITY OF CHICAGO (US) 2012-11-27 US claimed
CN-102206373-A Polypropylene composition with low linear expansion coefficient and preparation method thereof KINGFA SCIENCE & TECHNOLOGY CO 2011-10-05 CN claimed
JP-2010536785-A 2010-12-02 JP claimed
EP-2187736-A2 PLANT PATHOGEN RESISTANCE The University of Chicago (US) 2010-05-26 EP claimed
WO-2009055126-A2 PLANT PATHOGEN RESISTANCE THE UNIVERSITY OF CHICAGO (US) 2009-04-30 WO claimed
US-20090048312-A1 PLANT PATHOGEN RESISTANCE THE UNIVERSITY OF CHICAGO (US) 2009-02-19 US claimed