SCHEMBL8638409

SCHEMBL8638409

O=C(O)CCCCCCCCCCCCCCC(=O)O.[NaH]

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.92
LMNA P02545 3/20 0.92
NFKB1 P19838 1/20 0.92
PMP22 Q01453 1/20 0.92
SLC22A6 Q4U2R8 2/20 0.71
GPR84 Q9NQS5 8/20 0.71
FFAR1 O14842 2/20 0.71
FFAR4 Q5NUL3 2/20 0.71
PPARG P37231 7/20 0.67
PPARD Q03181 7/20 0.67
PPARA Q07869 7/20 0.67
HDAC11 Q96DB2 5/20 0.67
ALDH1A1 P00352 3/20 0.67
PTPN1 P18031 3/20 0.67
TLR2 O60603 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
MEN1 O00255 2/20 0.67
FABP4 P15090 2/20 0.67
ALOX15 P16050 2/20 0.67
KMT2A Q03164 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL306521 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Pimelic Acid SCHEMBL6756766 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Octanedioate SCHEMBL13732041 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Azelaic Acid SCHEMBL852025 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Octanedioate SCHEMBL188029 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
Azelaic Acid SCHEMBL2876285 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL8028939 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL11046983 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL6053549 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6
SCHEMBL28971884 1.00 TSHR (0.92) TSHRLMNANFKB1PMP22SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10150903-B2 Composition and use therof, oil-based drilling fluid and a method for raising shearing force of oil-based drilling fluid CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2018-12-11 US claimed
CN-104891511-A Method for synthesizing mesoporous silicon dioxide nanoparticles by using alkali-free method UNIV EAST CHINA NORMAL 2015-09-09 CN claimed
CN-104891511-A Method for synthesizing mesoporous silicon dioxide nanoparticles by using alkali-free method UNIV EAST CHINA NORMAL 2015-09-09 CN disclosed
EP-0709465-B1 Optical resolution for producing optically active alcohol NISSHIN OIL MILLS LTD (JP) 1998-08-05 EP disclosed
US-5696299-A Optical resolution for producing optically active alcohol THE NISSHIN OIL MILLS, LTD. (JP) 1997-12-09 US disclosed
EP-0709465-A2 Optical resolution for producing optically active alcohol The Nisshin Oil Mills, Ltd. (JP) 1996-05-01 EP disclosed