Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CA9 | Q16790 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | EGFR | P00533 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762995 | 1.00 | CA12 (0.59) | CA12CA1CA2CA9MAPT | |
| SCHEMBL28558448 | 0.87 | EGFR (0.77) | CA12CA1CA2CA9MAPT | |
| SCHEMBL28558447 | 0.87 | EGFR (0.77) | CA12CA1CA2CA9MAPT | |
| SCHEMBL28553002 | 0.83 | KLK7 (0.55) | CA12CA1CA2CA9MAPT | |
| SCHEMBL28552143 | 0.80 | CA12 (0.73) | CA12CA1CA2CA9MAPT | |
| SCHEMBL14354772 | 0.79 | EGFR (0.76) | CA12CA1CA2CA9MAPT | |
| SCHEMBL28912063 | 0.78 | EGFR (0.70) | MAPTKMT2AEGFRMEN1MAPK1 | |
| SCHEMBL28562106 | 0.78 | EGFR (0.70) | MAPTKMT2AEGFRMEN1MAPK1 | |
| SCHEMBL8996081 | 0.75 | EGFR (0.77) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8996038 | 0.75 | EGFR (0.77) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656372-B | P-phenylenediamine bridging compound and application thereof in preparation of medicines for treating sugar metabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114573476-B | Linear head-tail diamine bridging compound and application thereof in preparation of medicines for treating sugar metabolic disorder diseases | 广州药本君安医药科技股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114656371-B | 1, 4-cyclohexanediamine bridged compounds and their use in the treatment of disorders of glucose metabolism | 广州药本君安医药科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114656371-A | 1, 4-cyclohexanediamine bridged compound and application thereof in preparing medicament for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656372-A | P-phenylenediamine bridged compound and application thereof in preparation of medicines for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114573476-A | Linear head-tail diamine bridged compound and application thereof in preparing medicament for treating glycometabolism disorder diseases | 广州药本君安医药科技股份有限公司 | 2022-06-03 | — | — | CN | disclosed |