Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729395 | 0.81 | CNR2 (0.48) | CNR2BCHEACHECNR1OPRM1 | |
| SCHEMBL13041648 | 0.80 | TSHR (0.48) | CNR2TSHRMAPK1BCHEACHE | |
| Hydrochloric Acid SCHEMBL17416412 | 0.80 | CNR2 (0.47) | CNR2BCHEACHECNR1OPRM1 | |
| SCHEMBL7745377 | 0.80 | TSHR (0.50) | CNR2TSHRMAPK1BCHEACHE | |
| SCHEMBL6244917 | 0.80 | TSHR (0.50) | CNR2TSHRMAPK1BCHEACHE | |
| SCHEMBL2880129 | 0.80 | HDAC1 (0.47) | CNR2TSHRMAPK1BCHEACHE | |
| Hydrochloric Acid SCHEMBL16163415 | 0.79 | BCHE (0.46) | CNR2BCHEACHECNR1OPRM1 | |
| SCHEMBL6221079 | 0.78 | CNR2 (0.48) | CNR2BCHEACHECNR1OPRM1 | |
| SCHEMBL3732116 | 0.77 | ALOX5AP (0.48) | CNR2TSHRMAPK1BCHEACHE | |
| SCHEMBL3729168 | 0.76 | TSHR (0.76) | TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103306-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS | ASTRAZENECA UK LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |