Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 9/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876339 | 0.80 | CNR2 (0.49) | TSHRMAPK1CNR2BCHEACHE | |
| SCHEMBL13041648 | 0.79 | TSHR (0.48) | HDAC1TSHRMAPK1CNR2BCHE | |
| SCHEMBL7745377 | 0.79 | TSHR (0.50) | HDAC1TSHRMAPK1CNR2BCHE | |
| SCHEMBL6244917 | 0.79 | TSHR (0.50) | HDAC1TSHRMAPK1CNR2BCHE | |
| SCHEMBL3732116 | 0.76 | ALOX5AP (0.48) | HDAC1TSHRMAPK1CNR2BCHE | |
| SCHEMBL3729168 | 0.75 | TSHR (0.76) | TSHRMAPK1TP53POLBMAPT | |
| Hydrochloric Acid SCHEMBL16163295 | 0.74 | TSHR (0.74) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL6220202 | 0.72 | CNR2 (0.67) | CNR2BCHEACHECNR1 | |
| Hydrochloric Acid SCHEMBL16163415 | 0.71 | BCHE (0.46) | CNR2BCHEACHECNR1 | |
| SCHEMBL6221079 | 0.71 | CNR2 (0.48) | CNR2BCHEACHECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103306-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS | ASTRAZENECA UK LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |