Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742099 | 0.77 | DPP4 (0.56) | DPP4F2AOC3HTR2ATAAR1 | |
| SCHEMBL14455234 | 0.77 | DPP4 (0.56) | DPP4F2AOC3HTR2AADRA2A | |
| SCHEMBL2866367 | 0.77 | DPP4 (0.56) | DPP4F2AOC3HTR2AADRA2A | |
| SCHEMBL239938 | 0.74 | DPP4 (1.00) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL851654 | 0.74 | DPP4 (1.00) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL644767 | 0.74 | DPP4 (1.00) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL2067094 | 0.74 | DPP4 (1.00) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL150159 | 0.74 | DPP4 (1.00) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL1878642 | 0.74 | DPP4 (1.00) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL30802089 | 0.74 | DPP4 (0.52) | DPP4F2AOC3TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063347-A | Phosphine-1, 2-diphenyl ethylenediamine ligand with chiral benzene ring framework, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-05-05 | — | — | CN | claimed |
| CN-114426564-A | Chiral ferrocenyl phosphine-1, 2-diphenyl ethylene diamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-05-03 | — | — | CN | claimed |
| CN-114426564-B | Chiral ferrocene phosphine-1, 2-diphenyl ethylenediamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-09-08 | — | — | CN | disclosed |
| CN-116063347-A | Phosphine-1, 2-diphenyl ethylenediamine ligand with chiral benzene ring framework, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-116063347-A | Phosphine-1, 2-diphenyl ethylenediamine ligand with chiral benzene ring framework, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-116063347-A | Phosphine-1, 2-diphenyl ethylenediamine ligand with chiral benzene ring framework, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-114539327-A | Chiral tridentate imine P, N, N-ligand, preparation method and application in Cu-catalyzed asymmetric propargyl conversion | 中国科学院大连化学物理研究所 | 2022-05-27 | — | — | CN | disclosed |
| CN-114426564-A | Chiral ferrocenyl phosphine-1, 2-diphenyl ethylene diamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-05-03 | — | — | CN | disclosed |
| CN-114426564-A | Chiral ferrocenyl phosphine-1, 2-diphenyl ethylene diamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-05-03 | — | — | CN | disclosed |