Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14455234 | 1.00 | DPP4 (0.56) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL9425803 | 0.89 | CYP3A4 (0.62) | DPP4CYP3A4CYP2C19CYP2D6SLC6A2 | |
| SCHEMBL23716036 | 0.84 | AOC3 (0.50) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL9906120 | 0.83 | CYP3A4 (0.56) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL12260224 | 0.83 | CYP3A4 (0.56) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8147964 | 0.83 | CYP3A4 (0.56) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL2542748 | 0.83 | CYP3A4 (0.56) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL5475480 | 0.83 | CYP3A4 (0.56) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8945895 | 0.82 | IDO1 (0.46) | DPP4F2CYP3A4CYP2C19CYP2D6 | |
| Dimethylamine SCHEMBL2138001 | 0.80 | DPP4 (0.78) | DPP4F2CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105802196-B | A kind of high molecular material and preparation method thereof with double process shape-memory effect | 中山大学 | 2018-08-07 | — | — | CN | disclosed |
| US-9321045-B2 | Catalyst and process for synthesising the same | THE UNIVERSITY OF WARWICK (GB) | 2016-04-26 | — | — | US | disclosed |
| US-9181217-B2 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150290634-A1 | Catalyst and Process for Synthesising the Same | THE UNIVERSITY OF WARWICK (GB) | 2015-10-15 | — | — | US | disclosed |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-04 | — | — | US | disclosed |
| WO-2013141395-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2013-09-26 | — | — | WO | disclosed |
| EP-2623509-A1 | Method of producing an optically active amine compound by catalytic asymmetric hydrogenation using a ruthenium-diphosphine complex | Kanto Kagaku Kabushiki Kaisha (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-20130197234-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2013-08-01 | — | — | US | disclosed |
| US-7659409-B2 | 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20100029985-A1 | Process | AVECIA PHARMACEUTICALS LIMITED (GB) | 2010-02-04 | — | — | US | disclosed |
| EP-1741693-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOLS | Nagoya Industrial Science Research Institute (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20050107621-A1 | 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-05-19 | — | — | US | disclosed |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1512678-A1 | Process for preparing optically active nitro compounds and cyano compounds | Kanto Kagaku Kabushiki Kaisha (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1486493-A1 | 3-HYDROXY-3-(2-THIENYL)PROPIONAMIDE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING 3-AMINO-1-(2-THIENYL)-1-PROPANOL COMPOUND THEREFROM | Mitsubishi Chemical Corporation (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-20040176616-A1 | Process for producing optically active compound | KANTO KAGAKU KABUSHIKI KAISHA | 2004-09-09 | — | — | US | disclosed |
| EP-1439159-A1 | Process for producing optically active compound | Kanto Kagaku Kabushiki Kaisha (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-6686505-B2 | HYDROGENATION OF NITRO KETONE OR CYANO KETONE IN PRESENCE OF TRANSITION METAL COMPOUND CATALYST; AMINATION | KANTO KAGUKU KABUSHIKI KAISHA (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1308435-A2 | Process for producing optically active amino alcohols | Kanto Kagaku Kabushiki Kaisha (JP) | 2003-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107621-A1 | 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same | APEH, AADAC, KMO | DPP4 83/4885F2 1038/4885CYP3A4 107/4885 |
| US-20030171592-A1 | Process for producing optically active amino alcohols and intermediates therefore | ADH1A, NOS1, ADH5 | DPP4 4573/4885F2 2325/4885CYP3A4 195/4885 |
| US-20100029985-A1 | Process | ADH1A, ADH1C, AKR1C3 | DPP4 4788/4885F2 269/4885CYP3A4 25/4885 |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | HRH1, HRH4, RB1 | DPP4 4229/4885F2 3488/4885CYP3A4 1794/4885 |
| US-20150290634-A1 | Catalyst and Process for Synthesising the Same | CBR3, SPR, RNF5 | DPP4 3913/4885F2 2655/4885CYP3A4 518/4885 |
| US-20040176616-A1 | Process for producing optically active compound | OSTC, NPEPPS, PPOX | DPP4 1485/4885F2 3265/4885CYP3A4 77/4885 |
| US-20050101787-A1 | Process for preparing optically active nitro compounds and cyano compounds | NOS1, NOS2, NOX1 | DPP4 4252/4885F2 1289/4885CYP3A4 194/4885 |
| US-20130197234-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE COMPOUND | HRH3, TDO2, SRM | DPP4 3863/4885F2 2592/4885CYP3A4 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.